脑脊液置换治疗蛛网膜下腔出血临床观察

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目的:探讨内科治疗蛛网膜下腔出血的方法。方法:治疗组45例,腰穿放脑脊液,每次10~15ml,然后注入生理盐水 5~10ml,再放脑脊液再注入生理盐水,如此反复共置换脑脊液40~60ml,每1~2d置换一次,共3~5次。对照组37例,仅做腰穿,化验脑脊液协助诊断。全部病例均给降颅压、止血、抗纤溶、预防并发症等综合治疗。结果:治疗组疗效明显优于对照组。治疗组头痛症状缓解快,病程短,并发症少,6~11d脑压及脑脊液大多恢复正常。再出血2例,死亡1例,脑血管痉挛致脑梗塞1例,平均住院4周。对照组,头痛头晕症状持续时间长,甘露醇用量大、病程长,并发症多,脑压及脑脊液恢复多在3~4周,再出血8例,死亡4例,脑血管痉挛致脑梗塞偏瘫4例。不同程度脑积水伴智力减退3例,住院时间均在5周以上。结论:该方法疗效肯定,并发症少,操作简便,易于推广。 Objective: To explore the method of medical treatment of subarachnoid hemorrhage. Methods: In the treatment group, 45 cases were treated by lumbar puncture with cerebrospinal fluid (10-15ml each time), then 5 ~ 10ml of normal saline was injected into the cerebrospinal fluid and then normal saline was added into the cerebrospinal fluid. The cerebrospinal fluid was repeatedly cocultivated for 40-60ml once per 1-2 days, A total of 3 to 5 times. Control group, 37 cases, only to do lumbar puncture, cerebrospinal fluid test to help diagnose. All patients were given intracranial pressure, hemostasis, anti-fibrinolysis, complications and other comprehensive prevention and treatment. Results: The treatment group was significantly better than the control group. Treatment group headache symptoms relieved quickly, short course, fewer complications, 6 ~ 11d mostly intracranial pressure and cerebrospinal fluid returned to normal. Rebleeding in 2 cases, 1 case of death, 1 case of cerebral infarction caused by cerebral vasospasm, the average hospitalization for 4 weeks. In the control group, headache and dizziness symptoms persisted for a long time. The dosage of mannitol was large, the course of the disease was long, the complication was high. The recovery of cerebrospinal fluid and cerebrospinal fluid were mostly in 3 to 4 weeks. There were 8 cases of rebleeding, 4 cases of death, 4 cerebral infarction hemiparesis caused by cerebral vasospasm example. Different degrees of hydrocephalus with mental retardation in 3 cases, hospital stay in more than 5 weeks. Conclusion: The method is effective, less complications, easy to operate, easy to promote.
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