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应用氦-氖激光血管内照射(ILIB)方法治疗18例慢性乙型肝炎患者,结果显示丙氨酸转氨酶(ALT)、过氧化脂质(LPO)降低,P<0.01;而总超氧化物歧化萌(SOD)、锰超氧化物歧化酶(MnSOD)、铜锌超氧化物歧化酶(CuZnSOD)增高,同时50%~60%的病人HBeAg、HBVDNA转阴,且与患者临床症状好转相符合。结果还显示T淋巴细胞亚群CD8(Ts/Tc)、大颗粒淋巴细胞(LGL)提高(P<0.05~0.01),然而TH亚群变动不显著(P>0.05),提示ILIB具有免疫调节及抗病毒感染的作用。文中还讨论了ILIB治疗慢性乙型肝炎效应的机理,为乙型肝炎的治疗提供了一个新的方法。
18 patients with chronic hepatitis B were treated with helium-neon laser intravascular irradiation (ILIB). The results showed that ALT and LPO decreased, P <0.01; while total superoxide dismutase SOD, MnSOD and CuZnSOD were increased, while HBeAg and HBVDNA were negative in 50% -60% of patients, and the clinical symptoms were improved with phase meets the. The results also showed that the T lymphocyte subsets CD8 (Ts / Tc) and large granular lymphocytes (LGL) increased (P <0.05-0.01), however, the TH subsets did not change significantly (P> 0.05) Tip ILIB immune regulation and anti-viral infection role. The article also discussed the mechanism of ILIB treatment of chronic hepatitis B effect, provides a new method for the treatment of hepatitis B.