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在宿主细胞内,成熟的丙型肝炎病毒(HCV)包膜蛋白E1、E2滞留在内质网腔内,而不是在细胞质内和细胞膜上,曾有报道认为这与E1、E2的C端有关。作者利用拓扑法在理论上进一步证实了E1的C
In host cells, mature hepatitis C virus (HCV) envelope proteins E1 and E2 remain in the endoplasmic reticulum rather than in the cytoplasm and on the cell membrane, which have been reported to be related to the C-terminal of E1 and E2 . The author uses topology method to further confirm the theory of E1 C