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目的总结Krukenberg瘤患者的临床组织病理特点,分析影响肿瘤发生和预后的相关因素。方法回顾性分析25例Krukenberg瘤患者的临床组织病理特点,分析年龄、原发瘤直径、浸润深度、淋巴结转移、腹腔积液、转移瘤直径、单双侧及预后等,并进行多因素分析。结果本组患者1,2,3a生存率分别为60.0%(15/25),20%(5/25),12%(3/25);年龄、有无腹腔积液及治疗方式为影响预后的主要因素,而原发瘤直径、浸润深度、有无淋巴结转移,转移瘤直径、单双侧对预后的影响无统计学意义(P>0.05)。结论 Krukenberg瘤主要预后因素是年龄和治疗方式,手术可改善患者生存率。
Objective To summarize the clinical histopathological features of patients with Krukenberg’s tumor and analyze the related factors that influence the tumorigenesis and prognosis. Methods The clinical histopathologic features of 25 patients with Krukenberg’s tumor were retrospectively analyzed. Age, diameter of primary tumor, depth of invasion, lymph node metastasis, peritoneal effusion, diameter of metastasis, unilateral and bilateral and prognosis were analyzed. Multivariate analysis was performed. Results The 1,2,3a survival rates in this group were 60.0% (15/25), 20% (5/25), and 12% (3/25) respectively; age, presence or absence of peritoneal effusion, and treatment modality were prognostic factors. The main factors, but the primary tumor diameter, depth of invasion, with or without lymph node metastasis, metastasis of tumor diameter, unilateral and bilateral effects on prognosis was not statistically significant (P> 0.05). Conclusion The main prognostic factors of Krukenberg tumors are age and treatment methods. Surgery can improve the survival rate of patients.