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为观察甘利欣抗肝内胆汁郁积的作用，对５０例伴肝内胆汁郁积的各型病毒性肝炎患者，随机分为两组，治疗组２６例，使用甘利欣注射液治疗，对照组２４例，采用茵枝黄注射液治疗。分别观察其临床症状、生化指标的改变。结果发现，在改善皮肤瘙痒、降酶和清除与肝内胆汁郁积有关的生化参数方面，两组均存在显著性差异（Ｐ＜００５或Ｐ＜０．０１）。说明使用甘利欣治疗病毒性肝炎伴肝内胆汁郁积是一种有效实用的方法。
In order to observe the effect of Glycyrrhizin against intrahepatic cholestasis, 50 cases of viral hepatitis with intrahepatic cholestasis were randomly divided into two groups, the treatment group of 26 cases, the use of Gan Lixin injection, the control group of 24 patients , Yin Zhi Huang injection treatment. Observe the clinical symptoms and biochemical changes. The results showed that significant differences (P <005 or P <0.01) were found between the two groups in terms of improving pruritus, lowering of enzyme and biochemical parameters related to clearance of intrahepatic cholestasis. Description of the use of Glycyrrhizin treatment of viral hepatitis with intrahepatic cholestasis is an effective and practical method.