目的　探讨甲亢合并周期性麻痹的临床特点。方法　回顾性分析了 2 1例甲亢合并周期性麻痹患者的临床资料。结果　男性 2 0例 ,女性 1例。发作时均有不同程度的双下肢或四肢软瘫 ,伴有血钾降低的 18例。2 1例T3、T4 均高于正常。结论　甲亢周期性麻痹以年轻男性多发 ,补钾治疗可迅速改善症状 ,抗甲状腺治疗是控制甲亢周期性麻痹复发的关键 Objective To investigate the clinical features of hyperthyroidism complicated with periodic paralysis. Methods The clinical data of 21 patients with hyperthyroidism complicated with periodic paralysis were analyzed retrospectively. Results 20 males and 1 females. Attacks have different degrees of both lower limbs or limbs, paralysis, accompanied by decreased serum potassium in 18 cases. 21 cases of T3, T4 were higher than normal. Conclusions The frequent hyperthyroidism periodic paralysis occurs in young males. The treatment with potassium can rapidly improve the symptoms. Anti-thyroid treatment is the key to control recurrence of hyperthyroidism periodic paralysis