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目的 :研究围手术期输注异体全血或红细胞对非小细胞肺癌术后无病生存时间的影响 .方法 :回顾性调查了 70例接受了手术治疗的非小细胞肺癌患者 ,其中 5 3例 (75 .7% )患者接受了围术期输全血或红细胞悬液 .无病生存期分析采用多因素Cox回归模型 ,并绘制生存曲线 .结果 :Cox模型因素分析表明 ,影响预后的主要因素 (P <0 .0 5 )有分化程度、术后分期、术后辅助治疗措施 ;而包括围手术期输血等均非主要预后因素 (P >0 .0 5 ) ;但生存曲线显示 ,围手术期输血具有缩短非小细胞肺癌患者无病生存期的趋势 .结论 :围术期输血可能具有缩短非小细胞肺癌患者无病生存时间的趋势 ,外科医师应当尽量减少手术患者的输血机会
Objective: To study the effect of perioperative transfusion of whole blood or erythrocytes on the postoperative disease-free survival of non-small cell lung cancer.Methods: A retrospective study of 70 patients with non-small cell lung cancer undergoing surgery, of which 53 cases (75.7%) received perioperative whole blood transfusion or erythrocyte suspension.Multivariate Cox regression model was used to analyze the disease-free survival and the survival curves were drawn.Results: Cox model analysis showed that the main factors affecting the prognosis (P0.05), there was no significant difference between the two groups (P0.05), but there was no significant difference between the two groups (P0.05) Transient blood transfusion has a tendency to shorten the disease-free survival of patients with non-small cell lung cancer.Conclusion: Perioperative blood transfusion may shorten the disease-free survival time of patients with non-small cell lung cancer, surgeons should minimize the chance of blood transfusion in patients undergoing surgery