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目的:考察我院肾移植患者围手术期抗感染药物的应用情况及为临床提供用药参考;方法:查阅2006年1月-2007年12月我院肾移植患者病历254份,并对相关信息进行调查分析。结果:患者共应用了33种抗感染药物,金额比例最高的种类为其他β-内酰胺类与β-内酰胺酶抑制药复方制剂。用药频度排在第一位的为磺胺甲叶恶唑/甲氧苄啶片。共51名患者出现了感染并发症,最常见的为上呼吸道感染和肺部感染,其中15名患者的病历中附有病原学检测结果。结论:我院肾移植围手术期抗感染药物的应用基本合理。
Objective: To investigate the application of perioperative anti-infectives in patients with renal transplantation in our hospital and to provide reference for the clinical use of drugs.Methods: Check the records of 254 cases of renal transplant patients in our hospital from January 2006 to December 2007, and related information research analysis. Results: A total of 33 anti-infectives were administered to patients with the highest rates of other β-lactam and β-lactamase inhibitors. Frequency of medication ranked first for the sulfamethoxazole / trimethoprim tablets. A total of 51 patients developed complications of infection, the most common of which were upper respiratory tract infections and pulmonary infections, of which 15 were accompanied by an etiological test. Conclusion: The application of perioperative anti-infectives in renal transplantation in our hospital is reasonable.