论文部分内容阅读
目的 探讨促性腺激素释放激素激动剂 (GnRH -a)对子宫腺肌症合并不孕的疗效。方法 对 12例子宫腺肌症合并不孕者行GnRH -a治疗 ,同时加用甾体激素“反加疗法” ,部分病例应用辅助生殖技术。治疗前后用B超、核磁共振 (MRI)、血清CA12 5和生殖激素 (FSH、LH、E2 )及骨密度 (BMD)测定。结果 治疗后痛经等症状缓解 ,B超和MRI提示子宫腺肌病病灶基本消退 ,子宫大小 83 33% (10 / 12 )恢复正常 ,血CA12 5、FSH、LH、E2水平显著降低 (P <0 0 1) ,腰椎BMD无明显变化 (P >0 0 5 ) ,妊娠率达 75 0 %。结论 GnRH -a是治疗子宫腺肌病合并不孕的一种有效方法
Objective To investigate the effect of gonadotropin-releasing hormone agonist (GnRH-a) on infertility with adenomyosis. Methods 12 cases of adenomyosis with infertility line GnRH-a treatment, plus steroid hormone “anti-add therapy”, in some cases assisted reproductive technology. Before and after treatment with B ultrasound, MRI, serum CA12 5 and reproductive hormones (FSH, LH, E2) and bone mineral density (BMD) determination. Results The symptoms of dysmenorrhea were relieved after treatment. The lesions of adenomyosis were subsided by B ultrasound and MRI, and the levels of uterine adenomyosis were 83 33% (10/12), and the levels of serum CA12 5, FSH, LH and E2 were significantly decreased (P <0. There was no significant change in BMD of lumbar spine (P> 0.05), and the pregnancy rate reached 75%. Conclusion GnRH-a is an effective method for the treatment of adenomyosis with infertility