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对家兔实验性单纯疱疹病毒性角膜炎用多种黄精多糖制剂进行治疗,并与无环鸟苷治疗组及氯霉素组进行对照观察,结果表明,各种黄精多糖制剂组与氯霉素组比较,其治疗作用均有统计学意义(P<0.05),其中黄精多糖眼液滴眼配合黄精多糖注射液结膜下注射和黄精多糖眼液滴眼配合黄精多糖口服液口服的2组疗效优于无环鸟苷组(P<0.05)。而且接受黄精多糖制剂治疗的实验动物,其胸腺重量均超过其它两组(P<0.05)。提示黄精多糖制剂对家兔实验性单纯疱疹病毒性角膜炎的疗效,可能系通过提高实验动物免疫系统功能而获得。
The experimental herpes simplex virus keratitis in rabbits was treated with a variety of polygonatum polysaccharide preparations and compared with acyclovir treatment group and chloramphenicol group. The results showed that various polysaccharides and chloramphenicol preparation group The therapeutic effect was statistically significant in each group (P<0.05). Among them, the combination of Huangjing polysaccharide eye drops combined with Huangjing polysaccharide injection subconjunctival injection and Huangjiao polysaccharide eye drops combined with Huangjing polysaccharide oral liquid was superior. In the acyclovir group (P<0.05). Furthermore, the weight of thymus in experimental animals treated with Huangqin polysaccharide was higher than that in the other two groups (P<0.05). It is suggested that the efficacy of Huang Jing polysaccharide preparation on experimental herpes simplex virus keratitis in rabbits may be obtained by increasing the immune system function of experimental animals.