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经尿道前列腺切除的主要危险是术后感染。为了评价术前给单剂帚抗生素硫酸乙基紫苏霉素(Netilmicin suefate)对术后感染的预防作用,作者随机研究了100名(其中5人因术后严重血尿影响尿细菌学检在被淘汰)术前无菌尿的病人。95名病人分为对照(47名)和预防给药(48名)两组,两组病人在年龄、手术时间、切除组织大小、组织学检查和尿道感染史等均无明显差别。对照组术前1小时肌注1.5ml0.9％NaCl,给药组术前1小时肌注1.5ml含150mgNetilmicin溶液。用免疫酶学法测定对照组19人给药组20人尿中硫酸乙基紫苏霉素浓度。
Transurethral resection of the main risk of postoperative infection. In order to evaluate the prophylactic effect of a single dose of the antibiotic, Netilmicin suefate, on postoperative infection, the authors randomized 100 patients (5 of whom were tested for urine bacterial contamination after severe postoperative hematuria Elimination) Preoperative sterile urine of patients. Ninety-five patients were divided into control (n = 47) and prophylaxis (n = 48) groups. There was no significant difference between the two groups in terms of age, operation time, size of resected tissue, histological examination and history of urinary tract infection. The control group received intramuscular injection of 1.5ml0.9% NaCl 1h before operation, and the intramuscular injection of 1.5ml 150mgNetilmicin solution was given intraperitoneally 1 hour before the operation in the control group. Enzyme immunoassay was used to determine the concentration of ethylhosufomycin sulfate in urine of 20 people in the control group of 19 patients.