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患者男,33岁,诊断为获得性免疫缺陷综合征(艾滋病期)。在启动高效抗逆转录病毒治疗(HAART)后,CD4计数持续回升,病毒载量检测不到。至5个月时,出现咳嗽、恶心、淋巴结肿大、单发皮肤结节等,淋巴结活检病理证实为卡波西肉瘤。2个疗程化疗之后临床症状缓解,随访至今无复发。卡波西肉瘤可以作为免疫重建的一种临床表现,化疗能达到临床缓解,成功的抗病毒治疗有助于长期病情稳定。
Male patient, 33 years old, diagnosed with Acquired Immune Deficiency Syndrome (AIDS stage). After high-activity antiretroviral therapy (HAART) was started, the CD4 count continued to rise and the viral load was undetectable. To 5 months, there cough, nausea, lymph nodes, single skin nodules, lymph node biopsy pathology confirmed as Kaposi’s sarcoma. After 2 courses of chemotherapy, the clinical symptoms were relieved and no recurrence was observed up to now. Kaposi’s sarcoma can be used as a clinical manifestation of immune reconstitution, chemotherapy can achieve clinical remission, and successful antiviral therapy contribute to long-term stable disease.