系统性红斑狼疮(SLE)合并淀粉样变者较少见,兹报导1例如下:患者男,43岁,已有 SLE 病史20年。主要症状有关节炎、胸膜炎、心包炎、肢端动脉痉挛现象及乏力、发热、脱发等。LE 细胞和 ANA 均阳性。患者并有肾病综合征的表现(水肿、血浆白蛋白仅1.8克％,24小时尿蛋白达6.14克),肌酸酐廓清率83毫升/分。为了查明病人肾病变的性质,作了肾脏活检,并将所获肾组织作了以下各种检查:(1)HE 染色:显示有脉管膜性小结,包括淡染的无定形物质。有两 Systemic lupus erythematosus (SLE) with amyloidosis less common, it is reported as follows: The patient male, 43 years old, has a history of SLE for 20 years. The main symptoms of arthritis, pleurisy, pericarditis, acral artery spasms and fatigue, fever, hair loss and so on. LE cells and ANA were positive. Patients also had nephrotic syndrome manifestations (edema, plasma albumin, only 1.8 grams, 24 hours urine protein up to 6.14 grams), creatinine clearance rate of 83 ml / min. In order to ascertain the nature of the patient’s nephropathy, a kidney biopsy was made and the kidney tissue obtained was examined for various types of the following: (1) HE staining: revealed a membranous membranous nodules, including lightly stained amorphous material. There are two