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目的探讨非手术终止妊娠的方法、最佳给药途径及剂量。方法米非司酮总量150mg,配伍米索前列醇0.6mg对360例自愿要求使用药物终止妊娠的孕12～20周的妇女,采用三种不同给药途径终止妊娠,进行观察比较。结果米非司酮常规口服加米索前列醇外用给药,完全流产率高,胃肠道反应轻。结论使用米非司酮150mg,分次服用并配伍米索前列醇阴道后穹隆放置用于终止12～20周妊娠,恶心、呕吐等胃肠道反应发生率低,4h内流产率高,效果好。
Objective To explore the method of non-surgical termination of pregnancy, the optimal route of administration and dosage. Methods The total amount of mifepristone 150mg, with misoprostol 0.6mg on 360 cases of pregnant women who volunteered to use drugs to terminate pregnancy in 12 to 20 weeks, the termination of pregnancy by three different routes of administration were observed and compared. Results mifepristone conventional oral administration of misoprostol for external administration, high total abortion rate, gastrointestinal reaction light. Conclusion The use of mifepristone 150mg, taken in batches and misoprostol vaginal fornix placed for the termination of 12 to 20 weeks of pregnancy, nausea, vomiting and other gastrointestinal reactions with low incidence of abortion within 4h, the effect is good .