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Laca纯系成年雌雄小鼠,受了~(60)Coγ线950rad(剂量率82R/min)一次全身照射后,移植5×10~6同系而性别不同的小鼠骨髓细胞,60天活存率54.4％,照射对照组于12～15天内全部死亡。在移植前3天或移植后即刻分别肌肉注射0.25mg和0.05mg 3,17β棕榈酸椎二醇(简称“棕二”)或0.5mg丙酸睾丸酮(简称“丙睾”),可使活存提高到76.2％～86.4％。对造血组织脾脏,也有促进其恢复重量的趋势。若单纯应用“棕二”或“丙睾”对950rad照射小鼠未见有明显的防治作用。
The Laca pure line adult male and female mice were transplanted with 5 × 10 ~ 6 mice of the same lineage but different sex after one whole body irradiation at a dose of 950rad (dose rate of 82R / min) 54.4%, irradiation control group died within 12 to 15 days. Three days before transplantation or immediately after transplantation, intramuscular injection of 0.25mg and 0.05mg of 3,17β-dipalmitoyl palmitate (referred to as “brown two”) or 0.5mg of testosterone propionate (referred to as “testosterone”), can live Increase to 76.2% ~ 86.4%. The hematopoietic tissue spleen, but also to promote the recovery of its weight trend. If only the application of “Brown II” or “C testosterone” 950rad irradiated mice showed no significant prevention and treatment.