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1964～1983年在我科诊治宫颈鳞癌270例中,见有8例多发性原发癌,占2.9％。3例于宫颈癌治疗后2.5～4年发生外阴和阴道原位癌,4例于治疗后3～16年发生阴道原位癌,1例在宫颈原位癌治疗前4年患外阴癌行根治术。从女性生殖器官的发生学讨论了在同一致癌因素影响下,宫颈、阴道和外阴有发生多中心癌瘤的潜能。在一种原发性肿瘤治疗后的长期随访中应作全面细致的妇科检查,以期及早诊断。
1964 to 1983 in our department for diagnosis and treatment of cervical squamous cell carcinoma in 270 cases, see 8 cases of multiple primary cancer, accounting for 2.9%. 3 cases of vulvar and vaginal carcinoma occurred 2.5 to 4 years after treatment of cervical cancer, 4 cases of vaginal carcinoma in situ 3 to 16 years after treatment and 1 case of vulvar cancer treated 4 years before cervical carcinoma Surgery. From the female reproductive organogenesis study discussed under the influence of the same carcinogenic factors, cervical, vaginal and vulvar polycnsal tumors have the potential. In a long-term follow-up after a primary tumor treatment should be comprehensive and detailed gynecological examination, with a view to early diagnosis.