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对慢性阻塞性肺病氧疗后出现单纯高碳酸血症５０例患者的临床及血气资料进行分析，发现其中３４例氧疗后低氧血症改善但持续存在高碳酸血症，ＰａＣＯ２≥６．６７ｋＰａ，另１６例则高碳酸血症很快被纠正；顽固性高碳酸血症组中有１５例分别在持续低流量吸氧（１～２升／分）和停止吸氧３０分钟后进行血气对比分析。结果提示顽固性高碳酸血症可能系严重的气道阻塞所至。持续低流量吸氧可明显改善低氧血症，而对ＰａＣＯ２影响小。
Clinical data and blood gas data of 50 patients with simple hypercapnia after oxygen therapy of chronic obstructive pulmonary disease were analyzed. Among them, 34 patients with hypoxemia improved after oxygen therapy but persistent hypercapnia, PaCO2≥6.67kPa , And the other 16 cases of hypercapnia was corrected quickly; 15 cases of refractory hypercapnia group were continuous low-flow oxygen (1-2 liters / min) and stop oxygen 30 minutes after blood gas contrast analysis. The results suggest that intractable hypercapnia may be caused by severe airway obstruction. Continuous low-flow oxygen inhalation can significantly improve hypoxemia, while PaCO2 little effect.