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本文对扑热息痛泡腾冲剂和片剂进行了比较研究。泡腾冲剂和片剂在家兔体内吸收的特征参数Auc、Cm、Tm具有显著性差异(p 0.05)。泡腾冲剂和片剂对小鼠的镇痛作用试验以及对家兔的解热作用试验证明,当口服给药时,泡腾冲剂是一个易吸收,作用出现快,毒性也较小的新剂型。
This article compares effervescent effervescent granules and tablets. The characteristic parameters Auc, Cm and Tm of effervescent tablets and tablets in rabbits were significantly different (p <0.05). The analgesic effect of effervescent granules and tablets on mice and the antipyretic effect on rabbits prove that when orally administered, effervescent granules are a new dosage form that is easy to absorb, fast acting and less toxic .