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1983年9月对某大学新生随机抽取776名进行体检及静脉采血,凡SGPT正常者作为观察对象,建立队列,于3.5年(1987年4月)后再次体检及抽血检测。观察目前大学生在集体生活条件下乙肝传播的可能概率。本文采用ELISA法,专人检测,检测标志有乙肝表面抗原(HBsAg)、表面抗体(抗-HBs)、核心抗体(抗-HBc)、e抗原(HBeAg)、抗体(抗-HBe)。试剂均为上海市医化所提供。 结果 1983年9月759名同学(男性361、女性398)检测结果①乙肝总感染率男性(62.05％)高于女性(53.27％)(X~2=5.97p<0.05);②HBsAg阳性率男性也比女性高(X~2=4.86p<0.50),男女之比为1:55:1;③乙肝总感染率、HBsAg阳性率经标化后在上海市、上海效县及外省市,以及各系科中的分布均无差别。3.5年后共随访到708名,随访率为93.28％,其中男333(92.24％)、女375(94.22％)。观察结
In September 1983, a random sample of 776 freshmen from a university was taken to undergo a physical examination and venous blood sampling. All subjects with normal SGPT were selected as observers and a cohort was established. Physical examination and blood tests were performed again after 3.5 years (April 1987). To observe the current probability of undergraduates living under the conditions of hepatitis B transmission. In this paper, ELISA, hand detection, detection of hepatitis B surface antigen (HBsAg), surface antibody (anti-HBs), the core antibody (anti-HBc), e antigen (HBeAg), antibody (anti -HBe). Reagents are provided by the Shanghai Medical Institute. Results In September 1983, 759 students (361 males and 398 females) showed that the overall prevalence of hepatitis B was higher in males (62.05%) than females (53.27%) (X ~ 2 = 5.97p <0.05) (X ~ 2 = 4.86p <0.50). The ratio of male to female was 1: 55: 1. (3) The total infection rate of hepatitis B and HBsAg positive rate were standardized in Shanghai, Shanghai and other provinces and cities There is no difference in the distribution among departments. A total of 708 follow-up visits were made after 3.5 years, with a follow-up rate of 93.28%, of whom 333 were male (92.24%) and 375 (94.22%) were female. Observation conclusion