新生儿ABO溶血病(ABO-HDN)是早期新生儿高胆红素血症的主要原因,严重病例可发生胆红素脑病甚至死亡。近年来,我们应用单次大剂量人血免疫球蛋白静脉注射治疗新生儿ABO溶血病所致的高胆红素血症,减少胆红素脑病的发生及换血的需要,并取得了满意的疗效,现报告如下。1临床资料1.1 Neonatal ABO hemolytic disease (ABO-HDN) is the main cause of neonatal hyperbilirubinemia in early neonatal bilirubin encephalopathy and even death in severe cases. In recent years, we apply a single high-dose human immunoglobulin intravenous injection of neonatal ABO hemolytic disease caused by hyperbilirubinemia, reduce the occurrence of bilirubin encephalopathy and transfusion needs, and achieved satisfactory results The report is as follows. 1 clinical data 1.1