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目前全世界约有15%的育龄夫妇不育,男性不育是一种常见疾病,大约有50%的不孕症是由于男性因素,因此男性因素导致的不育已成为一个不容忽视的问题~([1]),而这多半又与染色体的异常相关~([2,3])。早期研究证实,男性不育患者的染色体异常发生率远高于正常生育人群~([4]),约有30%的男性不育患者被诊断为严重少精症或无精症,而这些患者都具有明显的遗传学异常,于此同时也有很大的可能将染色体异常传递给子代~([5])。本文就1例罕见的嵌合型
Currently, about 15% of the world’s infertility couples infertility, male infertility is a common disease, about 50% of infertility is due to male factors, so male factors lead to infertility has become a problem can not be ignored ~ ([1]), which is mostly related to chromosomal abnormalities ~ ([2,3]). Early studies have shown that the incidence of chromosomal abnormalities in male infertility is much higher than that of normal fertile people ([4]). About 30% of male infertility patients are diagnosed as having severe oligozoospermia or azoospermia, and these patients All have obvious genetic abnormalities, at the same time there is a great possibility that the chromosomal abnormalities will be passed on to the offspring (5). This article on a rare case of chimeric