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患者,女,77岁,2004年5月7日因股骨头坏死入院住骨科病房,入院后查肝肾功能正常,空腹血糖9.05mmol·L-1,5月13日做股骨头置换手术,5月14日空腹血糖为10.3mmol·L-1,餐后2h血糖为14.6mmol·L-1,即请内分泌科医生会诊,会诊后建议口服二甲双胍,0.25g,tid。当日中午饭后患者服用二甲双胍0.25g,2h后出现尿频症状,但未引起患者和医生的注意,晚饭后再次服用二甲双胍0.25g,结果尿频症状加重,直至尿失禁,到次日清晨4时左右小便失控症状减轻,但仍有尿频,故停药。停药后1d尿频症状消失,并改用胰岛素注射,血糖控制良好,出院。
Patients, female, 77 years old, May 7, 2004 hospitalized for orthopedic ward due to necrosis of femoral head, check liver and kidney function after admission, fasting blood glucose 9.05mmol·L-1, femoral head replacement surgery on May 13, 5 Fasting blood glucose on the 14th was 10.3mmol · L-1, 2h postprandial blood glucose was 14.6mmol·L-1, that endocrinologist consultation, after consultation recommended oral metformin, 0.25g, tid. After lunch on the day of patients taking metformin 0.25g, 2h after symptoms of frequent urination, but did not cause the patient and the doctor’s attention, taking metformin again after dinner 0.25g, the results of increased urinary frequency symptoms until urinary incontinence, to the next morning about 4 pm urine Loss of control symptoms, but there are still frequent urination, it is discontinued. Urine frequency symptoms disappeared on day 1 after discontinuation, and insulin infusion was used instead. Blood glucose was well controlled and discharged.