论文部分内容阅读
目的探讨孕妇血清中乙型肝炎病毒ＤＮＡ（ＨＢＶＤＮＡ）含量与胎儿宫内感染发生率的关系。方法用斑点杂交法检测１８５例乙型肝炎病毒表面抗原（ＨＢｓＡｇ）阳性孕妇血清中ＨＢＶＤＮＡ及新生儿ＨＢｓＡｇ。结果胎儿发生宫内感染与其母亲血清ＨＢＶＤＮＡ含量有关，随着孕妇血清中ＨＢＶＤＮＡ含量的增高，胎儿发生宫内感染的危险性也呈增高的趋势。结论孕妇血清ＨＢＶＤＮＡ含量升高是胎儿发生乙型肝炎病毒感染的重要因素之一。
Objective To investigate the relationship between serum HBV DNA (HBV DNA) and the incidence of intrauterine infection in pregnant women. Methods HBVDNA and HBsAg in sera of 185 pregnant women with positive hepatitis B virus surface antigen (HBsAg) were detected by dot blot hybridization. Results Fetal intrauterine infection and its mother’s serum HBVDNA content, with the serum HBVDNA levels increased, the risk of fetal intrauterine infection also showed an upward trend. Conclusion The increase of serum HBVDNA in pregnant women is one of the important factors in the occurrence of hepatitis B virus infection in the fetus.