目的研究原发性中枢神经系统淋巴瘤的MRI表现并分析淋巴瘤的病理基础。方法对15例患者MRI检查和病理检查资料进行调研,分析MRI和病理特征。结果 MRI结果显示,原发性中枢神经系统淋巴瘤包括了单发性12例,多发性3例,肿瘤影像多呈类圆形肿块或结节,有轻度水肿现象,MRI平扫T1WI多显示弱信号,无钙化、出血等现象。病理检查结果与MRI诊断结果存在显著差异。结论 MRI对原发性中枢神经系统淋巴瘤的术前诊断,需要在结合各种病史资料进行综合性分析的基础上进行鉴别诊断。 Objective To study the MRI findings of primary central nervous system lymphoma and to analyze the pathological basis of lymphoma. Methods Fifteen patients underwent MRI examination and pathological examination, and MRI and pathological features were analyzed. Results The MRI findings showed that the primary CNS lymphoma included 12 cases of solitary disease and 3 cases of multiple tumors. The tumors were mostly round lumps or nodules with mild edema and MRI plain T1WI Weak signal, no calcification, bleeding and so on. The results of pathological examination and MRI diagnosis have significant differences. Conclusion MRI preoperative diagnosis of primary central nervous system lymphoma, the need for a comprehensive analysis of a variety of medical history based on the differential diagnosis.