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目的：通过对影响甲状腺乳头状癌预后因素的研究，为治疗和预后提供直观的指标参数，对选择相应手术方案及术后的治疗均有指导意义。方法：本文采用微机关系数据库病理资料研究系统，对病理资料检索，取得我科外检病理中154例甲状腺乳头状癌的病理资料（均附5年以上的随访资料），对肿瘤的大小、浸润范围、有无淋巴细胞浸润、有无淋巴结转移对预后的影响进行分析、结果：甲状腺乳头状癌5年生存率为94.08％，10年生存率为80.71％，15年生存率为68.83％（用寿命表法计算入其它各相关因素均按≤5年及＞5年、≤10年及＞10年、≤15年及＞15年比较分析（用卡方计算）。其中肿瘤位于包膜内与肿瘤侵犯至包膜以外，各组比较均有极显著差异（P＜0.01）。肿瘤内及边缘有无淋巴细胞浸润，存活≤5年及＞5年有显著差异（P＜0.05），存活≤10年及＞10年、≤15年及＞15年均有极显著差异（P＜0．01）。结论：着重提示肿瘤包膜对癌肿的防御作用的重要性，肿瘤内及边缘有淋巴细胞浸润预示有良好的预后。
Objective: To study the prognostic factors affecting papillary thyroid carcinoma, and to provide intuitive index parameters for treatment and prognosis, and to guide the selection of the corresponding surgical plan and postoperative treatment. Methods: In this study, the pathological data retrieval system of the computer-based relational database was used to search for pathological data. The pathological data of 154 cases of thyroid papillary carcinoma were obtained from the external examination of our department (all with more than 5 years of follow-up data), and the size and infiltration of the tumor were obtained. The scope, presence or absence of lymphocytic infiltrate and lymph node metastasis were analyzed. The results showed that the 5-year survival rate of papillary thyroid carcinoma was 94.08%, the 10-year survival rate was 80.71%, and the 15-year survival rate was 68.83%. The life table method was calculated and entered into other relevant factors according to ≤5 years and>5 years, ≤10 years and>10 years, ≤15 years and>15 years comparison analysis (calculated by Chi-square). There was a significant difference between the tumors and the capsule (P<0.01), with or without lymphocytic infiltration in the tumors, and there was a significant difference in survival between ≤5 years and >5 years (P<0.05). There was a significant difference between 10 years and >10 years, ≤15 years, and >15 years (P<0.01).Conclusions: The importance of the protective effect of tumor capsules on cancers was emphasized, with lymphoids in and around tumors. Cell infiltration predicts good Good prognosis.