眼内新生血管病变是一类严贵影响视力的疾病。目前，除全视网膜激光光凝外，尚缺乏简易有效的治疗方法。近来，α－干扰素应用于实验及临床治疗新生血管病变取得了良好的效果。由于α－干扰素可以抑制细胞胸腺嘧啶脱氧核苷的转运与磷酸化，进一步抑制细胞ＤＮＡ的合成及其通过有丝分裂Ｓ期而抑制其增生。它可有效地抑制血管内支细胞的生长与迁移，故可抑制新生血管的发生；日前，新生血管的发病机理及α－干扰素的药理学作用机理尚未能从分子生物学水平完全阐述清楚，但其效果肯定。 Intraocular neovascular disease is a group of diseases that affect the eyesight. At present, in addition to the whole retina laser photocoagulation, there is a lack of simple and effective treatment. Recently, α-interferon used in experimental and clinical treatment of neovascular lesions achieved good results. As interferon-alpha inhibits the transport and phosphorylation of thymidine, further inhibits cellular DNA synthesis and suppresses its proliferation through mitotic S phase. It can effectively inhibit the growth and migration of intravascular cells, it can inhibit the occurrence of neovascularization; recently, the pathogenesis of neovascularization and pharmacological mechanism of α-interferon has not been fully elucidated from the molecular biology level , But its effect is certain.