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:【目的】评价99mTcMIBI与201T1肺肿瘤显像在原发性肺癌诊断中临床意义。【方法】28例肺癌患者进行了201T1早期(15min)与延迟(3h)肺肿瘤平面显像,其中23例有同期的99mTcMIBI显像资料;勾画各时相前位图像上病变部位(T)及对侧正常肺组织(N)的感兴趣区,计算摄取比值(T/N)及滞留指数[RI=(延迟T/N-早期T/N)×100/早期T/N)],并取病灶部位放射性较正常肺组织摄取明显增高为阳性指标进行定性分析。【结果】99m TcMIBI早期与延迟显像肉眼定性分析诊断肺癌的阳性率分别为8696%和7826%,201T1显像两者阳性率均为8929%;99mTcMIBI早期与延迟显像T/N分别为126±019与124±019,201T1为143±021和159±032,99mTcMIBI与201T1比较早期T/N之间与延迟T/N之间均有明显差异(t值分别为5538与733,P值均<0001);同时201T1显像所计算的滞留指数(1083±1180)%明显大于99mTcMIBI肺显像(-144±662)%,差异有显著意义(t=4307,P<0001)。【结论】99m TcMIBI与201T1肺显像在原发性肺癌的诊断中具有较高的阳性预测值,但肿瘤部位的滞留指数后者明显增高,提示201T1肺显像更具优越性,对于两者在肺癌淋巴结转移灶探测中的临床价值,有待更深入研究
: 【Objective】 To evaluate the clinical significance of 99mTcMIBI and 201T1 lung tumor imaging in the diagnosis of primary lung cancer. 【Methods】 Twenty-eight patients with lung cancer underwent planar imaging of 201T1 early (15min) and delayed (3h) lung tumors. Twenty-three of them had 99mTcMIBI imaging data in the same period. (T / N) and retention index (RI = (delayed T / N-early T / N) × 100 / early T / N) were calculated from the region of interest of the contralateral normal lung tissue Radioactive lesions than normal lung tissue uptake was significantly increased as a positive indicator of qualitative analysis. 【Results】 The positive rates of 99m TcMIBI in early diagnosis and delayed imaging in diagnosis of lung cancer were 8696% and 7826%, respectively, and the positive rates of 89T1 in 201T1 imaging were 99.2% and 99%. The early and delayed 99m TcMIBI T / N were 126 ± 019 and 124 ± 019,201T1 143 ± 021 and 159 ± 032,99mTcMIBI and 201T1 early T / N and delayed T / N were significantly different (t values were 5538 and 733, P values were < 0001). At the same time, the retention index (1083 ± 1180)% of 201T1 imaging was significantly higher than that of 99mTcMIBI lung imaging (-144 ± 662)%, the difference was significant (t = 4307, P <0001). 【Conclusion】 99m TcMIBI and 201T1 lung imaging have a higher positive predictive value in the diagnosis of primary lung cancer, but the latter is significantly higher in the tumor site, suggesting that the 201T1 lung imaging has more superiority. For both The clinical value of detection of lymph node metastasis in lung cancer remains to be further studied