生物标准物质是生物检定的工具,只有正确地研制和使用生物标准物质,才能使生物检定设计合理、结果可靠、结论正确。正确研制和使用生物标准物质的关键在于对生物标准物质性质的认识。本文就国际生物标准物质的历史及发展过程中存在的一些问题作一简要介绍。早在1890年,Von Behring 和 Kitasato 用白喉毒 Biological material is a biological verification tool, and only the correct development and use of biological material in order to make the biological test design a reasonable, reliable results, the conclusion is correct. The key to the proper development and use of biological reference materials lies in the understanding of the nature of biological reference materials. This article gives a brief introduction of some problems in the history and development of international biological material. As early as 1890, Von Behring and Kitasato used diphtheria