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为探讨牙龈组织中血栓素Ｂ２（ＴＸＢ２）和６－酮－前列腺素Ｆ１α（６－ｋｅｔｏ－ＰＧＦ１α）与牙周炎各临床指标的关系，用放射免疫测定法分析牙周炎患者龈组织中的ＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α含量，同时分析实验牙的龈沟液量（ＧＣＦ）、牙龈指数（ＧＩ）、牙周袋深（ＰＤ）和附着丧失（ＡＬ）与龈组织中ＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α的关系。结果表明牙周炎龈组织中ＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α与ＧＣＦ、ＰＤ、ＡＬ均呈显著正相关；牙周炎患者ＧＣＦ与ＰＤ、ＡＬ呈显著正相关；ＰＤ与ＡＬ呈非常显著正相关；ＧＩ与ＴＸＢ２、６－ｋｅｔｏ－ＰＧＦ１α及ＧＣＦ、ＰＤ、ＡＬ各指数无显著相关关系。牙周炎龈组织中ＴＸＢ２（ｙ）与ＧＣＦ（Ｘ１）、ＧＩ（Ｘ２）、ＰＤ（Ｘ３）、ＡＬ（Ｘ４）的线性回归方程为ｙ＝１０．８４＋０．９９Ｘ１＋７．１１Ｘ２＋１３．７２Ｘ３－０．４７Ｘ４；６－ｋｅｔｏ－ＰＧＦ１α与ＧＣＦ、ＧＩ、ＰＤ、ＡＬ的回归方程为ｙ＝２．３３＋２．５２Ｘ１－１．６３Ｘ２－１．８４Ｘ３＋１．５４Ｘ４。提示ＴＸＢ２和６－ｋｅｔｏ－ＰＧＦ１α可反映牙周炎的严重程度，与牙周炎各临床指标间的变化符合线性回归方程，证明ＴＸＢ２和６－ｋｅｔｏ－?
To investigate the relationship between TXB2 and 6-keto-PGF1α in gingival tissues and various clinical indicators of periodontitis, radioimmunoassay was used to analyze the expression of TXB2 and gingival tissues in patients with periodontitis TXB2 and 6-keto-PGF1α in the gingival tissues were measured. The GCF, GI, PD and AL in experimental teeth were also analyzed. The levels of TXB2 and 6-keto -PGF1α. The results showed that the levels of TXB2 and 6-keto-PGF1α in gingival tissues of periodontitis were significantly and positively correlated with GCF, PD and AL. There was a significant positive correlation between GCF and PD and AL in periodontitis patients. There was a significant positive correlation between PD and AL TXB2, 6-keto-PGF1α and GCF, PD, AL index no significant correlation. The linear regression equation of TXB2 (y) and GCF (X1), GI (X2), PD (X3) and AL (X4) in gingival tissues of periodontitis was y = 10.84 + 0.99X1 + 7.11X2 + 13.72X3-0.47X4; The regression equation of -keto-PGF1α with GCF, GI, PD, AL was y = 2.33 + 2.52X1-1.63X2-1.84X3 + 1.54X4. These results suggest that the levels of TXB2 and 6-keto-PGF1α reflect the severity of periodontitis, and the linear regression equation with the changes of clinical periodontitis shows that TXB2 and 6-keto-