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目的:研究高原地区高血压合并睡眠呼吸暂停综合征(SAS)对患者心血管系统的影响。方法:选择在我院住院的高血压合并SAS患者及单纯高血压患者各43例,通过睡眠呼吸监测、心脏彩超、心电图、Holter(动态心电图)以及24小时血压监测对两组患者的心脏结构、功能、心律失常及血压控制情况进行对比研究。结果:与对照组相比,高血压合并SAS组表现为右心增大、肺动脉压增高、左室舒张功能减低(P<0.05);室性早搏、右束支传导阻滞、窦性心动过缓及房室传导阻滞的发生率均增高(P<0.05);血压控制率降低(P<0.05)。结论:高原地区高血压合并SAS患者由于双重慢性缺氧导致心血管并发症发生风险增大,预后恶化,应及早治疗。
Objective: To investigate the effect of hypertension on sleep apnea syndrome (SAS) on cardiovascular system in high altitude area. Methods: A total of 43 hypertensive patients with hypertension and hypertension were enrolled in our hospital. The changes of heart structure, heart rate, heart rate, heart rate, Function, arrhythmia and blood pressure control were compared. Results: Compared with the control group, the patients with hypertension and SAS group showed right ventricular hypertrophy, increased pulmonary arterial pressure and decreased left ventricular diastolic function (P <0.05); premature ventricular contractions, right bundle branch block, sinus bradycardia The incidence of atrioventricular block was significantly higher (P <0.05) and the rate of blood pressure control was lower (P <0.05). CONCLUSIONS: Patients with hypertension and SAS in plateau should be treated early because of the increased risk of cardiovascular complications due to double chronic hypoxia.