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目的:观察自体血清联合抗病毒药物等治疗带状疱疹病毒性角膜炎的临床效果。方法:随机选取本院自2013年1月起至2015年4月间收治的40例带状疱疹毒性角膜炎作为研究对象,将其分为对照组(n=20)与观察组(n=20)。分别对对照组进行常规全身及局部的抗炎、抗病毒、营养神经药物等治疗,观察组将在前者基础上联合自体血清滴眼治疗。观察并记录两组患者的临床疗效及角膜炎症状、虹膜炎炎症的消失时间并做比较。结果:进行常规治疗联合自体血清治疗的观察组有效率明显高于进行常规治疗的对照组,且观察组治愈时间更短,差异有统计学意义(P<0.05)。结论:在常规治疗基础上应用自体血清治疗带状疱疹病毒性角膜炎具有快速缓解患者临床症状、缩短治疗时间,效果显著,值得应用推广。
Objective: To observe the clinical efficacy of autologous serum combined with antiviral drugs in the treatment of herpes zoster virus keratitis. Methods: 40 cases of herpes zoster keratitis admitted from January 2013 to April 2015 in our hospital were randomly divided into control group (n = 20) and observation group (n = 20) ). The control group were treated with general systemic and topical anti-inflammatory, antiviral and neurotrophic drugs. The observation group was treated with autologous serum eye drops on the basis of the former. The clinical efficacy and symptoms of keratitis and disappearance of iritis inflammation were observed and recorded. Results: The effective rate of the observation group treated with routine therapy combined with autologous serum was significantly higher than that of the control group treated routinely. The cure time of the observation group was shorter, the difference was statistically significant (P <0.05). Conclusion: The treatment of herpes zoster virus keratitis with autologous serum on the basis of routine treatment has the advantages of rapid remission of clinical symptoms and shortening of treatment time, and is worthy of promotion.