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目的:探讨精液白细胞与精子形态学参数之间关系。方法:对278例不育患者采用精子形态检测系统下人工修正方法进行精子形态分析,采用精液白细胞计数法检测精液白细胞,采用改良巴氏染色法分析精子顶体形态。结果:白细胞精子症组形态正常精子率和顶体完整率均低于非白细胞精子症组(P<0．05);形态正常精子率与精液白细胞浓度呈负相关关系(r=-0．243,P<0．01);顶体完整率与精液白细胞浓度亦呈显著负相关关系(r=-0．248,P<0．01)。结论:精液白细胞增多可能影响精子的形态和顶体的完整。
Objective: To investigate the relationship between sperm leukocyte and sperm morphological parameters. Methods: A total of 278 infertile patients were spermatozoa morphologically analyzed by artificial modification method. Sperm leukocytes were detected by semen leucocyte counting method. Acrosome morphology was analyzed by modified Papanicolaou staining. Results: The sperm morphology and sperm integrity rate of leukocyte sperm group were lower than that of non-leukocyte sperm group (P <0.05). There was a negative correlation between morphological normal sperm concentration and leukocyte concentration (r = -0.243 , P <0.01). There was also a significant negative correlation between acrosome integrity and leukocyte concentration (r = -0.248, P <0.01). Conclusion: Increased sperm leukocytosis may affect sperm morphology and acrosome integrity.