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随着北半球秋冬季节来临，以呼吸道飞沫和密切接触传播为主要途径的新型冠状病毒肺炎（新冠肺炎，2019冠状病毒病）给各国防控带来了新的挑战。本文从新冠病毒变异、全球流行形势、群体免疫问题、无症状感染对我国疫情防控的影响、疫苗的进展和治疗等方面对新冠肺炎流行及应对现状进行综述，以期为新形势下我国疫情防控策略的规划和调整提供借鉴。“,”As the approaching of autumn and winter in northern hemisphere, COVID-19, mainly transmitted through respiratory droplets and close contact, has posed new challenge to the countries across the world. This paper summarizes the current status of COVID-19 pandemic and related responses performed in terms of the variation of SARS-CoV-2, global situation reports, herd immunity and the influence of asymptomatic infection on COVID-19 prevention and control in China, as well as vaccine development progress and case treatment for the purpose of providing reference to further improve the COVID-19 prevention and control strategy in China.