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目的:探讨益气活血法防治经皮冠状动脉内介入治疗术(PCI)后再狭窄的临床疗效。方法:选取我院2014年2月—2016年2月收治的60例PCI术后患者,将患者按照随机数字对照法随机分为30例对照组和30例研究组。对照组运用西医治疗,所采用的药物为拜阿司匹林,研究组在对照组基础上通过益气活血法治疗。对比两组治疗后的临床疗效、心绞痛发作次数、心血管事件发生次数和血液流变学、血脂的变化。结果:研究组总有效率为90.0%,对照组总有效率为76.7%,两组对比具有显著统计学差异(P<0.05);研究组的心绞痛发作次数、心绞痛发作持续时间均低于对照组,两组差异具有显著统计学意义(P<0.05);两组在治疗后其全血黏度和红细胞积压、血脂均比治疗前明显降低,治疗后两组对比无显著统计学差异(P>0.05)。治疗结束后随访半年,研究组发生心血管事件的发生率显著低于对照组,两组对比具有显著统计学差异(P<0.05)。结论:益气活血法防治PCI术后再狭窄疗效显著,可以起到补益气血、通调经络之功效,能够显著促进血液循环,增强病变处血管通透性,降低心绞痛发作次数、心血管事件发生次数,改善血液流变学及血脂水平,适于临床推广使用。
Objective: To investigate the clinical efficacy of Yiqi Huoxue Therapy in prevention and treatment of restenosis after percutaneous coronary intervention (PCI). Methods: Sixty patients undergoing PCI from February 2014 to February 2016 in our hospital were selected and randomly divided into 30 control groups and 30 study groups according to the random number control method. In the control group, Western medicine was used. The drugs used were aspirin, and the study group was treated with Yiqi Huoxue Therapy on the basis of the control group. The clinical efficacy, the number of angina attacks, the number of cardiovascular events and the changes of blood rheology and blood lipids were compared between the two groups after treatment. Results: The total effective rate was 90.0% in the study group and 76.7% in the control group, with significant difference between the two groups (P <0.05). The number of angina attacks and the duration of angina pectoris in the study group were lower than those in the control group , The difference between the two groups was statistically significant (P <0.05). After treatment, the whole blood viscosity, hematocrit and blood lipids in both groups were significantly lower than those before treatment, and there was no significant difference between the two groups after treatment (P> 0.05 ). After six months of follow-up, the incidence of cardiovascular events in the study group was significantly lower than that in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Yiqi Huoxue Therapy has a significant effect in prevention and treatment of restenosis after PCI. It can replenish qi and blood and regulate the function of meridian. It can significantly promote blood circulation, enhance vascular permeability and reduce the number of angina attacks and cardiovascular events Occurrences, improve blood rheology and blood lipid levels, suitable for clinical promotion.