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会议于1991年10月24～26日在德国埃森召开,来自日本和德国的21名专家在会上作了报告,重点讨论了细胞骨架成份和细胞外基质结构和功能的特征、信息传递和恶性转化的分子机制以及细胞粘附力、浸润和转移的分子基础.Mayr博士根据最近证实的磷脂酰4,5-二磷酸肌醇〔PtdIns(4,5)P_2)与肌动蛋白结合蛋白凝胶溶胶素和Profilin的相互作用,探讨了细胞膜和胞液中的磷酸肌醇在细胞骨架及染色质重排中的潜在作用.1,4,5三磷酸肌醇〔Ins(1,4,5)P_3〕核受体的发现以及敏感的〔Ins(1,4,5)P_3〕从分离核释放钙
The conference was held in Essen, Germany from October 24th to 26th, 1991. Twenty-one experts from Japan and Germany made reports at the meeting, focusing on the characteristics of cytoskeletal components and extracellular matrix structure and function, information transmission, and The molecular mechanism of malignant transformation and the molecular basis of cell adhesion, infiltration and metastasis. Dr. Mayr’s recently confirmed phosphatidyl 4,5-bisphosphoinositide [PtdIns(4,5)P 2 ) and actin-binding protein coagulation The interaction between gelsolin and Profilin explores the potential role of phosphoinositides in cytoskeleton and chromatin rearrangement in cell membranes and cytosol. 1,4,5-trisphosphate Inositol [Ins (1,4,5) The discovery of P 3 ) nuclear receptors and sensitive [Ins(1,4,5)P_3] releases calcium from the isolated nucleus