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目的观察双水平无创正压通气(BiPAP)对煤工尘肺(CWP)合并呼吸衰竭的治疗作用。方法将56例煤工尘肺合并呼吸衰竭的患者随机分成治疗组(32例)和对照组(24例),比较两组治疗前后血气分析指标及临床症状改善情况。结果治疗组经无创正压通气治疗后临床症状及血气分析指标恢复正常,呼吸频率下降,心率下降,辅助呼吸肌活动明显减轻和消失,与对照组的血气分析指标及临床疗效比较,差异有显著性(P<0.01),结论双水平无创正压通气在煤工尘肺(CWP)合并呼吸衰竭的治疗中依从性强,解除呼吸肌疲劳,纠正呼吸衰竭,疗效肯定。
Objective To observe the therapeutic effect of bi-level noninvasive positive pressure ventilation (BiPAP) on coal worker’s pneumoconiosis (CWP) with respiratory failure. Methods Fifty-six patients with pneumoconiosis and respiratory failure were randomly divided into treatment group (32 cases) and control group (24 cases). The blood gas analysis indexes and clinical symptoms before and after treatment were compared between two groups. Results After treatment with noninvasive positive pressure ventilation, the clinical symptoms and blood gas analysis indexes of the treatment group returned to normal, the respiratory rate decreased, the heart rate decreased, the activity of the auxiliary respiratory muscle significantly reduced and disappeared. There was a significant difference between the treatment group and the control group in blood gas analysis and clinical efficacy (P0.01) .Conclusion The double-level noninvasive positive pressure ventilation has strong compliance in the treatment of coal worker’s pneumoconiosis (CWP) with respiratory failure, relieving respiratory muscle fatigue and correcting respiratory failure.