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用静脉注射丙种球蛋白 ( IVIG) 40 0～ 6 0 0 mg/( kg·次 ) ,首次用药后三天重复一次 ,配合抗生素治疗新生儿败血症 2 0例 ,治疗后患儿 Ig G及其亚类迅速提高 ,峰值为 Ig G:1 3.1 6± 1 .72 g/L,Ig G:6 .93± 2 .79g/L,Ig G2 :3.1 6± 1 .72 g/L,Ig G3:0 .5 9± 0 .2 9g/L,Ig G4:0 .42±0 .0 4g/L。治疗后 1 0天 ,IVIG组患儿的 Ig G及亚类均高于对照组 ,即抗生素与血浆组 ,尤以早产儿显著。Ig G组病死率 1 4.3% ,对照组死率 83.3% ,经统计学处理 u=2 .493,P<0 .0 5 ,有显著差别 ,且交叉感染率、体温稳定时间 ,两组之间均有显著差异
Intravenous injection of gamma globulin (IVIG) 40 0 ~ 600 mg / (kg · times), repeated three days after the first medication, with antibiotics treatment of neonatal sepsis 20 cases of children with Ig G and sub-treatment With a rapid increase of IgG: 1 3.1 6 ± 1 .72 g / L, Ig G: 6 .93 ± 2 .79 g / L, Ig G2: 3.1 6 ± 1 .72 g / L, Ig G3: 0 .5 9 ± 0.29g / L, Ig G4: 0.42 ± 0. 04g / L. At 10 days after treatment, IgG and its subgroups in IVIG group were higher than that in control group, namely antibiotics and plasma group, especially in premature children. The mortality of Ig G group was 4.3%, while that of the control group was 83.3%. The difference was statistically significant (u = 2.493, P <0.05), and the rates of cross-infection, body temperature stabilization time There are significant differences