目的探讨应用经皮冠状动脉腔内成形术（ＰＴＣＡ）治疗复杂冠状动脉病变的效果。方法５例冠心病患者经选择性冠状动脉造影证实为复杂冠状动脉病变即Ｂ型或Ｃ型病变者，采用Ｇｒｕｅｎｔｚｉｇ等建立的方法进行ＰＴＣＡ。结果１２处冠状动脉病变扩张成功１０处，成功率为８３．３％，其余两处病变一处因球囊未能通过狭窄部，另一处因术中患者发生严重的心律失常而未行扩张。术后患者的症状均得以缓解或消失。结论ＰＴＣＡ也适用于治疗复杂冠状动脉病变，且疗效较好，但危险性较大，并发症较多。 Objective To investigate the effect of percutaneous transluminal coronary angioplasty (PTCA) on complex coronary lesions. Methods Five patients with coronary heart disease were confirmed by selective coronary angiography as complicated coronary artery lesion type B or C, and the method of Gruentzig et al was used to perform PTCA. Results Twelve coronary lesions were successfully expanded in 10 lesions, with a success rate of 83.3%. One of the other two lesions did not pass through the stenosis due to the failure of the balloon and another did not expand due to severe arrhythmia in the patients . Postoperative patient symptoms have been alleviated or disappeared. Conclusion PTCA is also suitable for the treatment of complex coronary lesions, and the curative effect is better, but the risk is higher and there are more complications.