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目的:探讨机械通气治疗重症手足口病患儿的效果。方法:对35例重症手足口病患儿在应用常规药物治疗的同时予机械通气,根据病情调整呼吸机参数,观察通气前后临床症状及相关指标变化,并记录患儿住院天数、机械通气时间、转归及并发症发生等情况。结果:35例患儿平均住院时间(12.44±2.29)d,平均机械通气时间(3.34±1.44)d,共有30例患儿治愈或好转,机械通气后患儿体温、呼吸、心率、血压值及血氧饱和度较治疗前均有显著改善(P<0.05)。结论:重症手足口病患儿应仔细密切关注病情变化,经常规治疗后如症状不能改善,须尽早使用机械通气治疗,同时予以药物及对症支持处理。
Objective: To investigate the effect of mechanical ventilation on children with severe hand-foot-mouth disease. Methods: 35 children with severe HFMD were treated with conventional medical therapy while ventilated. The parameters of ventilator were adjusted according to the condition. The clinical symptoms and related indexes before and after ventilation were observed. The days of hospitalization, duration of mechanical ventilation, Outcome and complications occurred. Results: The average length of stay (12.44 ± 2.29) days and mean duration of mechanical ventilation (3.34 ± 1.44) days in 35 children were higher than those in the control group. A total of 30 children were cured or improved. The body temperature, respiration rate, heart rate, Oxygen saturation than before treatment were significantly improved (P <0.05). Conclusion: Children with severe hand-foot-mouth disease should pay close attention to the changes of the disease. If symptoms can not be improved after routine treatment, they should be treated with mechanical ventilation as soon as possible and treated with drugs and symptomatic support.