包括直接法和间接法2种。前者直接测定研究对象血或尿中所服用药物的浓度及代谢产物来评定依从性,对不能直接测定原药物或代谢产物者,也可在原药中加入某种便于检测的指示剂(如维生素B_2和荧光素)供检测依从性用。间接法则通过直接向患者询问,根据所考核药物的疗效或药片计数来衡量依从性。其中药 Including the direct method and indirect method 2 kinds. The former directly determine the study of blood or urine to take the drug concentration and metabolites to assess compliance, who can not directly measure the original drug or metabolite, but also in the original drug to add some easy to detect the indicator (such as vitamin B_2 And fluorescein) for detection of compliance. Indirect rule by directly asking the patient, according to the assessment of drug efficacy or tablet count to measure adherence. Its medicine