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最近,ZhengbinYao和FrancoisFossiez先后报道了从活化的记忆型CD4+T细胞中鉴定了一种新的细胞因子,命名为人白细胞介素-17(hIL-17)。hIL-17CDNA的开放读码框(ORF)编码-个155氨基酸的蛋白,N-末端有-个19个氨基酸的疏水信号肽序列,成熟有活性的hIL-17为136个氨基酸构
Recently, Zhengbin Yao and Francois Fossiez successively reported that a new cytokine was identified from activated memory CD4 + T cells and named human interleukin-17 (hIL-17). The open reading frame (ORF) of hIL-17 cDNA encodes a protein of 155 amino acids with a 19 amino acid hydrophobic signal peptide at its N-terminus and a mature, active hIL-17 of 136 amino acids