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本文探讨一氧化氮、超氧化物歧化酶（ＳＯＤ）与急性脑血栓形成的关系。选择急性脑血栓形成期患者３０例，其中症状进展期１３例，症状达高峰后６小时以内者１７例。另选２８例性别、年龄构成相似的健康人作对照。测定血清中一氧化氮，ＳＯＤ和丙二醛含量。结果发现：急性脑血栓形成时一氧化氮、ＳＯＤ含量均显著降低（ｐ＜０．０５），丙二醛含量显著增高（ｐ＜０．０１），一氧化氮与ＳＯＤ显著正相关（ｒ＝０．８４０６，ｐ＜０．００１）。提示一氧化氮、ＳＯＤ含量降低与急性脑血栓形成有关，它们之间存在相互作用。
This article discusses the relationship between nitric oxide, superoxide dismutase (SOD) and acute cerebral thrombosis. Thirty patients with acute cerebral thrombosis were selected, of which 13 were advanced in symptoms and 17 were within 6 hours after the peak of symptoms. Another 28 healthy subjects with similar sex and age were selected as controls. Determination of serum nitric oxide, SOD and malondialdehyde content. The results showed that the levels of nitric oxide and superoxide dismutase (SOD) in acute cerebral thrombosis were significantly decreased (p <0.05), MDA content was significantly increased (p <0.01), NO was positively correlated with SOD (r = 0.8406, p <0.001). Prompted nitric oxide, reduced SOD content and acute cerebral thrombosis related, there is an interaction between them.