论文部分内容阅读
近年来，电喷雾质谱作为“软电离”质谱新技术广泛应用于生命科学领域［１，２］，１９９１年Ｇａｎｅｍ等［３］首次利用电喷雾质谱（ＥＳＩ－ＭＳ）对溶液中特异性免疫蛋白质－药物复合物进行了研究．目前生物酶－底物／抑制剂、ＤＮＡ－药物、蛋白质－配体及生物大分子...
In recent years, electrospray ionization mass spectrometry is widely used in the field of life science as a new technology of “soft ionization” mass spectrometry [1, 2]. In 1991, Ganem et al [3] first used electrospray ionization mass spectrometry (ESI- - Drug complexes were studied. Current biological enzymes - substrates / inhibitors, DNA-drugs, protein-ligands and biological macromolecules ...