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近年来,电喷雾质谱作为“软电离”质谱新技术广泛应用于生命科学领域[1,2],1991年Ganem等[3]首次利用电喷雾质谱(ESI-MS)对溶液中特异性免疫蛋白质-药物复合物进行了研究.目前生物酶-底物/抑制剂、DNA-药物、蛋白质-配体及生物大分子...
In recent years, electrospray ionization mass spectrometry is widely used in the field of life science as a new technology of “soft ionization” mass spectrometry [1, 2]. In 1991, Ganem et al [3] first used electrospray ionization mass spectrometry (ESI- - Drug complexes were studied. Current biological enzymes - substrates / inhibitors, DNA-drugs, protein-ligands and biological macromolecules ...