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目的探讨脐动脉血p H值、脑电图对新生儿缺氧缺血性脑病(HIE)监测的合理性。方法选取2013年8月~2014年12月在我院分娩的无严重畸形的1018例新生儿作为研究对象,观察其脐动脉血p H值与HIE的关系,并随机选择352个新生儿生后12h内进行脑电图检查,观察其脑电图结果与HIE的关系。结果 1018例新生儿脐动脉血p H平均值7.26±0.08,HIE有19例,在4组不同脐动脉血p H中HIE的发生率比较差异显著,有统计学意义(χ2=399.36,P<0.01)。在352例新生儿进行脑电图检查中,有19例HIE,脑电图正常的328例中有3例HIE,脑电图异常的24例中有16例HIE,两组比较差异显著,有统计学意义(χ2=189.343,P<0.01)。结论对存在产前产时高危因素的新生儿应常规查脐动脉血p H值,尽早行脑电图检查,以提高新生儿缺氧缺血性脑病诊断的准确率。
Objective To investigate the rationality of umbilical arterial blood (p H) and electroencephalogram (EEG) in monitoring neonatal hypoxic-ischemic encephalopathy (HIE). Methods A total of 1018 newborns without serious malformations who were delivered in our hospital from August 2013 to December 2014 were selected as study objects. The relationship between p H value and umbilical arterial blood HUV was observed and 352 neonates were randomly selected EEG within 12h to check its EEG results and the relationship between HIE. Results The average p H value of umbilical artery in 1018 newborns was 7.26 ± 0.08 and 19 in HIE. There was significant difference in the incidence of HIE in p H between 4 umbilical arterial groups (χ2 = 399.36, P < 0.01). Of the 352 neonates who underwent EEG examination, there were 19 HIEs, 3 of 328 patients with normal EEG, and 16 of 24 patients with EEG abnormalities. There were significant differences between the two groups Statistical significance (χ2 = 189.343, P <0.01). Conclusion For neonates with high risk factors of prenatal delivery, umbilical arterial blood pH value should be routinely checked and EEG examination should be performed as early as possible to improve the diagnostic accuracy of neonatal hypoxic-ischemic encephalopathy.