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目的:探讨美敏伪麻溶液治疗儿童慢性鼻窦炎的有效性和安全性。方法:68例慢性副鼻窦炎患儿随机分为治疗组、对照组,2组均给予阿莫西林/克拉维酸钾分散片、标准桃金娘油肠溶胶囊口服、布地奈德鼻喷雾剂喷鼻。治疗组口服儿童美敏伪麻溶液,对照组口服鼻窦炎口服液,均连服7d后观察2组患儿咳嗽、流涕、鼻塞、清嗓、头痛等症状缓解情况,体征主要是观察鼻窦邻近组织的红、肿、压痛及鼻涕倒流入咽部,中鼻道有无脓液。同时观察不良反应发生情况。结果:治疗组的临床疗效较对照组有显著改善(P<0.01);不良反应发生率分别为4.41%,5.58%,治疗组与对照组比较差异无显著性(P>0.05)。结论:美敏伪麻治疗儿童慢性副鼻窦炎的临床疗效肯定,早期缓解症状,改善患儿生活质量,安全性佳。
Objective: To investigate the effectiveness and safety of Minmin pseudoephedrine solution in treating children with chronic sinusitis. Methods: Sixty-eight children with chronic sinusitis were randomly divided into treatment group, control group and two groups were given amoxicillin / clavulanate dispersible tablet, standard myrtle oil oral capsule, budesonide nasal spray Burning nose. Children in the treatment group were given oral administration of Minxin Pseudo Maize solution and oral liquid of oral administration of sinusitis in the control group. All patients in the treatment group were relieved of cough, runny nose, nasal congestion, clear throat and headache after 7 days of continuous oral administration. The signs were mainly observed in the vicinity of the sinus Organized red, swollen, tender and nose back into the pharynx, no or pus in the nasal passages. At the same time observe the occurrence of adverse reactions. Results: The clinical efficacy of the treatment group was significantly improved compared with the control group (P <0.01). The incidence of adverse reactions were 4.41% and 5.58% respectively. There was no significant difference between the treatment group and the control group (P> 0.05). Conclusion: The clinical efficacy of pseudoepimethamine in the treatment of chronic sinusitis in children is affirmative. It can relieve the symptoms early and improve the quality of life in children with good safety.