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目的对消炎止痒搽剂与消炎止痒散体外抑菌作用进行比较,为消炎止痒散改剂型研究提供实验基础,同时为消炎止痒搽剂消炎杀菌,燥湿止痒的临床功效提供一定的实验依据。方法采用对倍稀释法检测消炎止痒搽剂改剂型前后对细菌的抑制作用。结果消炎止痒搽剂对白色念珠菌的MIC为1/32;对铜绿假单胞菌的MIC为1/32;对金黄色葡萄球菌的MIC为1/512;对表皮葡萄球菌的MIC为1/512,均小于消炎止痒散对相应细菌的MIC。结论消炎止痒搽剂改剂型后对以上四种细菌的抑制作用优于消炎止痒散,为其改剂型研究和临床应用提供了一定的实验依据。
Objective To compare the antibacterial and antipruritic pruritus with antiphlogistic and antipruritic powder in vitro, and to provide experimental basis for the study of anti-inflammatory and antipruritic dispersant and modified dosage form. At the same time, it provides anti-inflammatory and antipruritic antipruritic agents for anti-inflammatory, anti-inflammatory and anti-itching effects. The experimental basis. Methods The double dilution method was used to detect the inhibitory effect of anti-inflammatory and antipruritic tincture before and after changing the dosage form. Results The MIC of antiphlogistic and antipruritic tincture for Candida albicans was 1/32; the MIC for Pseudomonas aeruginosa was 1/32; the MIC was 1/512 for Staphylococcus aureus; the MIC was 1 for Staphylococcus epidermidis. / 512, are smaller than the MIC of the corresponding bacteria. Conclusion The antibacterial and antipruritic agent has better inhibitory effect on the above four bacteria than the antiphlogistic and antipruritic powder, which provides a certain experimental basis for the study of modification and clinical application.