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临床应用输血来补充术中失血,对恢复血容量、改善携氧功能以保证手术顺利进行是必要的.肿瘤病人的免疫功能状况与疾病的发生、发展及预后有密切关系.1982年Burrows等回顾性研究提出了围手术期输血能影响癌肿病人的预后.本研究运用免疫组化方法对T淋巴细胞亚群进行检测,前瞻性观察胃癌患者输血后细胞免疫功能的变化规律,探讨其变化可能发生的机制,为临床肿瘤病人慎用输血提供理论依据.
Clinical application of blood transfusion to supplement intraoperative blood loss is necessary to restore blood volume and improve oxygen carrying function to ensure smooth operation. The immune function of cancer patients is closely related to the occurrence, development and prognosis of the disease. Burrows et al., 1982 Sexual studies suggest that perioperative blood transfusion can affect the prognosis of patients with cancer. In this study, immunohistochemistry was used to detect T-lymphocyte subsets, prospectively observe the changes of cellular immune function after transfusion in gastric cancer patients, and explore possible changes. The mechanism of occurrence provides a theoretical basis for clinical tumor patients to use blood transfusions with caution.