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目的:了解机关干部高尿酸血症人群分布情况,分析体质指数(BMI)、血脂异常、饮酒、饮食习惯以及高嘌呤食物与其患病率的相关性。方法:以2008年度珠海市干部体检人群为研究对象,向其发放调查问卷,了解其饮食结构、劳动强度、运动、饮酒等生活习惯,并分别测定其BMI、血尿酸(UA)、血糖(Glu)、血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平。结果:珠海市干部人群高尿酸血症总患病率为35.42%,并随年龄增长而上升,有年轻化的趋势,以中老年人为主,其中男性患病率(43.74%)显著高于女性(15.39%)。高尿酸血症人群并发脂肪肝、超重或肥胖(BMI≥24)、高TC血症、高TG血症、LDL-C增高、HDL-C降低的患病率远远高于非高尿酸血症人群(P<0.05)。经常摄入高嘌呤饮食者高尿酸血症的患病率明显增高。结论:干部体检人群高尿酸血症患病率随年龄增长而上升,有年轻化的趋势,并与性别、超重或肥胖、血脂异常、高嘌呤食物呈显著正相关性。
OBJECTIVE: To understand the distribution of hyperuricemia among cadres and analyze the correlation between body mass index (BMI), dyslipidemia, alcohol consumption, eating habits, and the prevalence of high purine foods. Methods: Taking Zhuhai cadres’ medical examination population in 2008 as the research object, questionnaires were distributed to them to understand their dietary habits, labor intensity, exercise and drinking habit. The BMI, blood uric acid (UA), blood glucose ), Total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) Results: The total prevalence of hyperuricemia in Zhuhai cadres was 35.42%, and increased with age. The prevalence was younger, mainly in middle-aged and elderly people, of which the male prevalence rate (43.74%) was significantly higher than that of women (15.39%). Hyperuricemia in patients with fatty liver complicated by overweight or obesity (BMI ≥ 24), hypercholesteremia, hypercholesterolemia, elevated LDL-C, HDL-C decreased prevalence was significantly higher than non-hyperuricemia Population (P <0.05). The prevalence of hyperuricemia with high-purine diet was significantly higher. Conclusion: The prevalence of hyperuricemia in cadres’ medical examination population increases with age, tends to be younger and has a significant positive correlation with gender, overweight or obesity, dyslipidemia and high purine foods.