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目的 :为了解小儿肺炎流感嗜血杆菌 (HI)临床感染情况。方法 :对确诊为肺炎的 5 8例学龄前期儿童及 2 0例健康儿童 ,取痰液或咽拭子取咽喉深部分泌物 ,同时采用半套式聚合酶链反应和HI培养法进行HI病原学检测。结果 :半套式PCR检测结果肺炎组检出 14/ 5 8(2 4.1% ) ,健康组检出 3/ 2 0 (15 % ) ;HI培养结果肺炎组阳性 12 / 5 8(2 0 .7% )、健康组阳性 1/ 2 0 (5 % )。经用洛欣、氧哌嗪青霉素、先锋必、西力欣及氟嗪酸治疗全部痊愈。结论 :流感嗜血杆菌感染在小儿肺炎中占重要地位 ,开展肺炎HI病原学研究可提高对HI感染的认识 ,并可为治疗提供可靠依据。
Objective: To understand the clinical infection of children pneumonia Haemophilus influenzae (HI). Methods: Fifty-eight preschool children diagnosed with pneumonia and twenty healthy children were taken sputum or throat swab to take the deep throat secretions, and the half-nested PCR and HI culture were used for HI etiology Detection. Results: The results of semi-nested PCR showed that in the pneumonia group, 14/58 (21.4%) were detected in the pneumonia group and 3/20 (15%) in the healthy group. The results of HI culture were 12/58 (20.7% %), Healthy group positive 1/2 0 (5%). With Losin, piperacillin penicillin, Pioneer will be, Xili Xin and ofloxacin all the treatment of healed. Conclusion: Haemophilus influenzae infection plays an important role in pediatric pneumonia. Carrying out the aetiological study of pneumonia can improve the understanding of HI infection and provide a reliable basis for the treatment.