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目的观察注射用奥扎格雷钠配合针刺疗法治疗急性脑梗死的疗效。方法将60例诊断明确的急性脑梗死患者随机分为2组:治疗组32例,给予注射用奥扎格雷钠80mg+5%GS250ml静脉滴注,每天1次,共用16d,同时于48h后给予针刺治疗,每日1次,共14d;对照组给予舒血宁注射液20ml+5%GS250ml静脉滴注,每天1次,连用16d。按临床神经功能缺损程度评分标准于治疗前和治疗后16d进行疗效评定。结果治疗组总有效率与对照组比较差异有统计学意义(96.88%vs78.57%,P<0.05);治疗组治疗后神经功能缺损程度评分明显低于对照组(6.32±3.44vs10.23±4.20,P<0.05)。结论注射用奥扎格雷钠配合针刺疗法治疗急性脑梗死疗效满意,且无明显不良反应。
Objective To observe the efficacy of sodium ozagrel for injection combined with acupuncture in the treatment of acute cerebral infarction. Methods Sixty patients with definite diagnosis of acute cerebral infarction were randomly divided into two groups: treatment group (n = 32) received intravenous injection of ozagrel sodium 80mg + 5% GS250ml intravenously once daily for 16 days and given 48 hours later Acupuncture treatment, 1 day, a total of 14d; control group given Shuxuening injection 20ml +5% GS250ml intravenous infusion, once daily, once every 16d. According to the clinical neurological deficit score standards before and 16d after treatment efficacy evaluation. Results The total effective rate in the treatment group was significantly different from that in the control group (96.88% vs78.57%, P <0.05). The score of neurological deficit in the treatment group was significantly lower than that in the control group (6.32 ± 3.44 vs10.23 ± 4.20, P <0.05). Conclusion Ozagrel sodium injection with acupuncture treatment of acute cerebral infarction with satisfactory results, and no significant adverse reactions.